Desarrollo de un escritorio digital para la captura, transcripción y gestión multimodal e interactiva de documentos manuscritos

[EN] This Master Thesis presents the design and implementation of the human-computer interface for the multidisciplinary project titled "Captura, transcripción y gestión multimodal e interactiva de documentos manuscritos". The objective of the interface is to help the user to manipulate the system, so it will be easy, intuitive and efficient. It has been developed a basic visualization and document management system, that allows the user to interact with the different parts of the system, as the document capture, processing, edition, printing, and storage[ES] El presente trabajo final de Máster consiste en el diseño e implementación de la interfaz humanocomputador para el proyecto multidisciplinar titulado “Captura, transcripción y gestión multimodal e interactiva de documentos manuscritos”. Dicha interfaz tiene como objetivo facilitar al usuario la utilización del sistema, de forma que pueda realizar las tareas de dicho proyecto de una forma sencilla, intuitiva y eficaz. Para ello se ha diseñado un sistema básico de visualización y gestión de documentos, que permite interaccionar con las distintas partes del sistema, como son la captura de documentos, su procesamiento, edición, impresión y almacenamiento.Vicente Parra, FJ. (2013). Desarrollo de un escritorio digital para la captura, transcripción y gestión multimodal e interactiva de documentos manuscritos. http://hdl.handle.net/10251/44381Archivo delegad

Impacto de la capitalización del gasto en I+D en Cantabria. Comparativa internacional

RESUMEN: En el marco central del SCN-1993/SEC-1995, los gastos en investigación y desarrollo se consideran consumo intermedio, es decir, gastos corrientes que benefician a la producción únicamente durante el ejercicio en curso. Esto contradice la propia naturaleza de la I+D, cuyo objetivo es mejorar la producción en ejercicios futuros. Con el fin de resolver los problemas conceptuales y prácticos que conlleva el registro de la I+D como formación de capital, como primer paso, la Unión Europea propuso a sus estados miembros realizar una serie de estudios para la estimación de los principales parámetros de la Cuenta satélite de la I+D antes de implantar el nuevo SEC-2010 en el año 2014. En este trabajo se describe por un lado las características de los sistemas de las principales Cuentas Satélite de I+D publicadas y, a continuación, el método seguido para realizar la capitalización del gasto de I+D en Cantabria. Final-mente, se comparan los resultados regionales con los obtenidos en los diferentes países.ABSTRACT: Within the central framework of the SCN-1993/SEC-1995, expenditure on R&D is considered intermediate con-sumption, that is to say, running costs that improve production during the current fiscal year solely. That is in contra-diction with the very same nature of the R&D, whose main aim is to improve production on future fiscal years. With the aim of working out the conceptual problems that the registration of R&D as a part of capital formation entails, as a first step, the EU proposed the Member States to carry out several studies to make an estimate of the main parame-ters of the R&D satellite accounts prior to the implementation of the new SEC-2010 in 2014. This paper describes the most relevant features included in the systems of the main R&D Satellite accounts already published alongside with the methodological approach followed in order to calculate R&D capitalization in Cantabria. We conclude this work by making a comparison between regional and national result

Comunicar en inglés: diseño y ejecución de una asignatura transversal para la internacionalización de la docencia

Depto. de Periodismo y Comunicación GlobalDepto. de Periodismo y Nuevos MediosFac. de Ciencias de la InformaciónFALSEsubmitte

El recurso Pixton como herramienta TIC de innovación docente desde una perspectiva multidisciplinar: historia, geografía, lengua y matemáticas

Memoria ID-051 Ayudas de la Universidad de Salamanca para la innovación docente, curso 2020-2021

Una propuesta de estructura de coordinación docente horizontal y vertical para la Universidad Politécnica de Cartagena (UPCT)

[ESP] La UPCT no disponía de una estructura generalizada de coordinación docente hasta el presente curso 2012 -2013. Un equipo docente ha trabajado en el diseño de un modelo completo de coordinación, revisando numerosas publicaciones, incorporando actuaciones que ya funcionan de manera puntual en la UPCT y ensayando nuevos mecanismos de coordinación. El modelo establece órganos de coordinación, metodologías concretas y un nuevo listado reducido de competencias genéricas. La propuesta contempla todos los aspectos relevantes de la coordinación docente y puede adaptarse a las características de cada centro. [ENG] During the course 2012-2013, a team of expe1is from the Technical University of Cartagena (UPCT) has designed and developed a model for vertical and horizontal teaching coordination. The work included compiling and analyzing models from other Universities, selecting some already-working methodologies, and developing new ones. The designed model includes a new list of generic skills and coordination structures and too Is that fít the coordination needs of any UPCT Centre

Cuentos del Olivar

En este apasionante viaje tenemos las puertas abiertas para todo aquel que se quiera sumar, ya sea trabajando en pos de la difusión de la cultura ligada al olivo o disfrutando de lecturas como las que se recogen en este libro, que seguro les depara un sabroso disfrute y les descubre una cultura del olivar que tiene a sus espaldas varios milenios de historia. Les deseo que paladeen cada uno de estos relatos, que conforman un excelente aperitivo literario.Área de Historia del Art

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Role of age and comorbidities in mortality of patients with infective endocarditis

[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children

We found that 19 (10.4%) of 183 unvaccinated children hospitalized for COVID-19 pneumonia had autoantibodies (auto-Abs) neutralizing type I IFNs (IFN-alpha 2 in 10 patients: IFN-alpha 2 only in three, IFN-alpha 2 plus IFN-omega in five, and IFN-alpha 2, IFN-omega plus IFN-beta in two; IFN-omega only in nine patients). Seven children (3.8%) had Abs neutralizing at least 10 ng/ml of one IFN, whereas the other 12 (6.6%) had Abs neutralizing only 100 pg/ml. The auto-Abs neutralized both unglycosylated and glycosylated IFNs. We also detected auto-Abs neutralizing 100 pg/ml IFN-alpha 2 in 4 of 2,267 uninfected children (0.2%) and auto-Abs neutralizing IFN-omega in 45 children (2%). The odds ratios (ORs) for life-threatening COVID-19 pneumonia were, therefore, higher for auto-Abs neutralizing IFN-alpha 2 only (OR [95% CI] = 67.6 [5.7-9,196.6]) than for auto-Abs neutralizing IFN-. only (OR [95% CI] = 2.6 [1.2-5.3]). ORs were also higher for auto-Abs neutralizing high concentrations (OR [95% CI] = 12.9 [4.6-35.9]) than for those neutralizing low concentrations (OR [95% CI] = 5.5 [3.1-9.6]) of IFN-omega and/or IFN-alpha 2

Geodivulgar: Geología y Sociedad 2018

Depto. de Geodinámica, Estratigrafía y PaleontologíaFac. de Ciencias GeológicasFALSEsubmitte